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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13L All Species: 15.15
Human Site: S741 Identified Species: 27.78
UniProt: Q71F56 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71F56 NP_056150.1 2210 242602 S741 K Q G T E K D S L K K N K S E
Chimpanzee Pan troglodytes XP_001138050 2188 240763 F721 F V E G D E E F L F P D K K D
Rhesus Macaque Macaca mulatta XP_001112106 2210 242628 S741 K Q G T E K D S L K K N K S E
Dog Lupus familis XP_534693 2280 250152 S810 K Q G T E K D S L K K N K S E
Cat Felis silvestris
Mouse Mus musculus Q6JPI3 2207 241740 S736 K Q G T E K D S L K K N K S E
Rat Rattus norvegicus NP_001101807 1374 149708
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 F703 F V D G D V E F L F P D N K K
Chicken Gallus gallus XP_415317 2195 241321 L718 K L V A E K D L L K K N K S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 I656 R T G G Q D G I V S I T E M M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 S936 C K E T S K S S G G N S S G G
Honey Bee Apis mellifera XP_393643 1982 216109 Q555 E I Y L E N E Q S L R C L Y D
Nematode Worm Caenorhab. elegans Q93442 2862 325119 G1091 E R I A V P G G V G S L V E I
Sea Urchin Strong. purpuratus XP_001203054 1127 123639
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.7 99.2 93.3 N.A. 92.4 57.7 N.A. 53.5 86.4 N.A. 50.2 N.A. 24.8 33.9 21.2 25.6
Protein Similarity: 100 69.3 99.6 94.7 N.A. 95.7 59.9 N.A. 69.7 92.5 N.A. 66.4 N.A. 41.5 50.5 38.5 35.1
P-Site Identity: 100 13.3 100 100 N.A. 100 0 N.A. 6.6 73.3 N.A. 6.6 N.A. 20 6.6 0 0
P-Site Similarity: 100 46.6 100 100 N.A. 100 0 N.A. 33.3 73.3 N.A. 33.3 N.A. 33.3 33.3 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 8 0 16 8 39 0 0 0 0 16 0 0 16 % D
% Glu: 16 0 16 0 47 8 24 0 0 0 0 0 8 8 39 % E
% Phe: 16 0 0 0 0 0 0 16 0 16 0 0 0 0 0 % F
% Gly: 0 0 39 24 0 0 16 8 8 16 0 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 8 0 0 8 0 0 0 8 % I
% Lys: 39 8 0 0 0 47 0 0 0 39 39 0 47 16 8 % K
% Leu: 0 8 0 8 0 0 0 8 54 8 0 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 8 39 8 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 16 0 0 0 0 % P
% Gln: 0 31 0 0 8 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 8 0 8 39 8 8 8 8 8 39 0 % S
% Thr: 0 8 0 39 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 16 8 0 8 8 0 0 16 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _